Timeline: Key moments in Brad Pitt and Angelina Jolie's relationship

Actress Angelina Jolie has filed for a divorce from actor Brad Pitt after 12 years together including two years of marriage, the end for one of Hollywood's most glamorous and powerful couples. Below is a timeline of key moments in the A-list couple's relationship over the years: - January 2005: Brad Pitt and "Friends" star Jennifer Aniston separate amid rumors that he and Jolie had an affair while filming the upcoming spy action thriller "Mr and Mrs Smith." Neither party confirmed the rumors. - April 2005: Photos appear in media of Pitt with Jolie and her adopted Cambodian son Maddox, vacationing together in Kenya.